The whole aspirin for miscarriages thing needs more evidence and studies. There are some studies, one of which is
http://humrep.oxfordjournals.org/cgi...ull/15/10/2220 carried out by a London Medical Team which have been investigating this.
Aspirin is an antiplatelet agent. There are 3 main components to the blood, which are all produced by the bone marrow - red blood cells which carry oxygen, white blood cells which fight infection and platelets which help the blood to clot. Aspirin inactivates cyclooxygenase 1 (COX-1) an enzyme found on platelets and stops them being able to clot the blood effectively. This is why aspirin is often used to 'thin the blood' in people with heart disease to lessen the risk of blood clots in their coronary arteries.
Pregnant women are also more likely to form clots. Platelets are only one of the mechanisms of clotting: there is also a much more hugely complicated mechanism with loads of different 'clotting factors' being involved. More of these are produced during pregnancy making blood clots more likely.
The above study is aimed at looking at whether thinning the blood will make a difference to placental thrombosis - blood clots in the placenta which stop the baby getting the blood supply and therefore nutrients from mum. The study didn't show any benefit from taking aspirin in recurrent early miscarriage. The study did show more live births in people taking low dose aspirin who had had previous late miscarriages however the numbers were uneven (should be a 50/50 divide between the 2 groups being looked at and there were 189 taking aspirin and only 61 not taking aspirin) which may have influenced the results. The authors say that taking aspirin for every recurrent early miscarriage isn't justified but do say that investigating women who are predisposed to blood that clots more easily (e.g smokers) for aspirin is being looked into and that they are looking at aspirin in women with late miscarriages.
Remember, NSAIDS (the group of drugs aspirin belongs to) can be harmful in pregnancy. By the same token that aspirin could be helpful if placental thrombosis is the problem, it could also cause haemorrhage (bleeding) in the placenta/baby which could be equally harmful. It would make you more likely to bleed more at delivery and has been associated with heart defects.
I'd talk it over with your Obstetrician Jacqui - they'll be able to tell you more in detail than I can and help you make the right decision for you and your future bub
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