Anyone Been HighRisk For Downs But Refused Amnio? - Page 2

Jelly_Tot · Oct 11th, 2009, 16:37 PM

Quote:

Originally Posted by Szaffi

Hi!

We are also in high risk for DS and refused amnio. I had two detailed scans, and no other indication was seen. Both times however, the doctors said that it doesn't mean that you can't have a baby with DS. Sometimes, there is just no sign on the ultrasound.

I've been worrying about it quite a lot, though I keep telling myself that we're in the 99.4%... Do you know what your specific number was? Was it based only on the blood test or did they take into account the nucheal translucency?

We have a 1 in 210 chance,

It was just the blood results and obviously my age and that i am a smoker and all the usual things they take into account to get the result xx

Szaffi · Oct 12th, 2009, 02:53 AM

I wouldn't worry then too much. Normally a "clear" ultrasound makes your chances twice as good - so something like 1:420. Our first test was 1:159, which got reduced to 1:232 on account of the clear ultrasound. I repeated the blood-test, and the second time, it was 1 : 450 - tells me how unreliable the screening is.

We decided that we'll live with those odds, and see what happens, as we wouldn't have terminated anyways, even in case of DS. Now that my due date is getting nearer, I'm getting again a bit anxious, but I guess it is part of the job description...

Becky_Mummy2B · Oct 12th, 2009, 03:01 AM

there are no guarantees in life either way... the tests (other than the amnio) are predictors, not diagnostic tests, so chances are, you'll be absolutely fine! not that that makes worrying any less. xxxxxxxxxxxxxxxxxxxxxxxxxxxx

surprise no5 · Oct 12th, 2009, 06:04 AM

This happened to me in 2007, my 16 week bloods came back as 1:150 so I was immediately offered an amnio which i refused. For me the risk of mc was still higher than the risk of ds, I looked at it as that was still only a 0.5% chance that anything was wrong. I mentioned my result to the sonographer when I went for my 20 week scan so she had a look for what she called 'soft markers'. These are things like head shape, femur length, nose, thumbs, heart and brain. She said all these things looked normal so my risk was much lower - she did ensure she pointed out that there WAS still a chance of ds though. It all turned out well for me, Lockie was born on 17th June 2007, very healthy and lively

I don't regret turning down the amnio at all and due to knowing there was a higher risk of ds I read lots of info etc to be prepared just incase. I think if my risk had been very high (1:5 for example) I may have decided to go ahead, am just hoping results come back ok this time xx

Aidedhoney · Oct 12th, 2009, 07:56 AM

Quote:

Originally Posted by surprise no5

This happened to me in 2007, my 16 week bloods came back as 1:150 so I was immediately offered an amnio which i refused. For me the risk of mc was still higher than the risk of ds, I looked at it as that was still only a 0.5% chance that anything was wrong. I mentioned my result to the sonographer when I went for my 20 week scan so she had a look for what she called 'soft markers'. These are things like head shape, femur length, nose, thumbs, heart and brain. She said all these things looked normal so my risk was much lower - she did ensure she pointed out that there WAS still a chance of ds though. It all turned out well for me, Lockie was born on 17th June 2007, very healthy and lively

I don't regret turning down the amnio at all and due to knowing there was a higher risk of ds I read lots of info etc to be prepared just incase. I think if my risk had been very high (1:5 for example) I may have decided to go ahead, am just hoping results come back ok this time xx

Surprise no5 is right, i had an amnio(not for downs) and they look for soft markers, these range from the presence of a nasal bone to golf balls on the heart.
I am sure if any of these were seen at your scan you would have been informed.
Wishing you well xxx

Marleysgirl · Oct 12th, 2009, 08:23 AM

Hi there,

I think I hold the record for the scariest Downs score so far on B&B - after blood tests, I was rated at 1 in 5. We still refused the amnio, taking the positive attitude of having a 4 in 5 chance of a baby without Downs, and being prepared to love the baby regardless. Andrew was born extremely prem, but is confirmed as having no chromosome disorder.

I had many u/sound scans due to IUGR, and the consultant did check for soft markers for Downs because of my score. The only marker he found (other than small size) was a short Femur Length. However, through his research clinic he has found that many of the IUGR babies have demonstrated a short FL with no Downs, and he's actually going to document back that FL & Downs shouldn't necessarily be linked in IUGR babies.

chocaholic · Oct 12th, 2009, 11:11 AM

Quote:

Originally Posted by Marleysgirl

Hi there,

I think I hold the record for the scariest Downs score so far on B&B - after blood tests, I was rated at 1 in 5. We still refused the amnio, taking the positive attitude of having a 4 in 5 chance of a baby without Downs, and being prepared to love the baby regardless. Andrew was born extremely prem, but is confirmed as having no chromosome disorder.

I had many u/sound scans due to IUGR, and the consultant did check for soft markers for Downs because of my score. The only marker he found (other than small size) was a short Femur Length. However, through his research clinic he has found that many of the IUGR babies have demonstrated a short FL with no Downs, and he's actually going to document back that FL & Downs shouldn't be linked in IUGR babies.

Glad to hear Andrew was born fit and well. Do you happen to know what constitutes a short femur length? And sorry to sound ignorant but what is IUGR?

Thanks xx

Marleysgirl · Oct 12th, 2009, 12:02 PM

Quote:

Originally Posted by chocaholic

Glad to hear Andrew was born fit and well. Do you happen to know what constitutes a short femur length? And sorry to sound ignorant but what is IUGR?

Ah well, there's a question. There are probably tables on t'internet that give the average FL for gestational week, but that is on the presumption of an average growth baby! I would say, in reassurance, that if it had been noted at the time of your scan, it would have been mentioned, along with another offer of an amnio. (They kept offering them to me right up to birth!)

IUGR = intra uterine growth disorder. Posh name for small for gestational age.

nellis10 · Oct 13th, 2009, 06:30 AM

Hi Hunnie!

With my first I did the tests and got a 1 in 95 chance of down's. It devastated us, but we decided against going for Amnio, and although the rest of the pregnancy was tinged with worry about the possibility, we had a very healthy boy who is now a 5yr old cheeky monkey!

blackthickpea · Oct 14th, 2009, 15:00 PM

i was sent for my quad test at 15 weeksconfirmed gestational age by ultrasound. at the lab the tech used my LMP date which I advised her not to use cause it would put me at 21.6 weeks when was actually 15. i have very irregular periods due to polycystic ovaries anyway the test came back positive for downs. My doc is being an ass about it. I was told that it came back positive because of the wrong gestational age. i did 2 anomally scans at 20weeks by different specialist but they both came back normal. What do you ladies think? i live in the caribbean and we donot have expertise like the states, united kingdom or Canada. ladies please let me know what you all think. thanksI am so worried I am now 33 weeks

Oct 12th, 2009, 02:53 AM	#12
Szaffi Pregnant (Expecting) Chat Happy BnB Member Join Date: Jun 2009 Location: Brussels, Belgium Posts: 1,959	I wouldn't worry then too much. Normally a "clear" ultrasound makes your chances twice as good - so something like 1:420. Our first test was 1:159, which got reduced to 1:232 on account of the clear ultrasound. I repeated the blood-test, and the second time, it was 1 : 450 - tells me how unreliable the screening is. We decided that we'll live with those odds, and see what happens, as we wouldn't have terminated anyways, even in case of DS. Now that my due date is getting nearer, I'm getting again a bit anxious, but I guess it is part of the job description...

Status: Offline

Oct 12th, 2009, 03:01 AM	#13
Becky_Mummy2B Mum (Mom) Chat Happy BnB Member Join Date: Jun 2009 Location: Bolton Posts: 1,224	there are no guarantees in life either way... the tests (other than the amnio) are predictors, not diagnostic tests, so chances are, you'll be absolutely fine! not that that makes worrying any less. xxxxxxxxxxxxxxxxxxxxxxxxxxxx

Status: Offline

Oct 12th, 2009, 06:04 AM	#14
surprise no5 Pregnant (Expecting) Active BnB Member Join Date: Aug 2009 Location: Somerset Posts: 337	This happened to me in 2007, my 16 week bloods came back as 1:150 so I was immediately offered an amnio which i refused. For me the risk of mc was still higher than the risk of ds, I looked at it as that was still only a 0.5% chance that anything was wrong. I mentioned my result to the sonographer when I went for my 20 week scan so she had a look for what she called 'soft markers'. These are things like head shape, femur length, nose, thumbs, heart and brain. She said all these things looked normal so my risk was much lower - she did ensure she pointed out that there WAS still a chance of ds though. It all turned out well for me, Lockie was born on 17th June 2007, very healthy and lively I don't regret turning down the amnio at all and due to knowing there was a higher risk of ds I read lots of info etc to be prepared just incase. I think if my risk had been very high (1:5 for example) I may have decided to go ahead, am just hoping results come back ok this time xx

Status: Offline

Oct 12th, 2009, 08:23 AM	#16
Marleysgirl Mum (Mom) Chat Happy BnB Member Join Date: Mar 2009 Location: Manchester Posts: 2,469	Hi there, I think I hold the record for the scariest Downs score so far on B&B - after blood tests, I was rated at 1 in 5. We still refused the amnio, taking the positive attitude of having a 4 in 5 chance of a baby without Downs, and being prepared to love the baby regardless. Andrew was born extremely prem, but is confirmed as having no chromosome disorder. I had many u/sound scans due to IUGR, and the consultant did check for soft markers for Downs because of my score. The only marker he found (other than small size) was a short Femur Length. However, through his research clinic he has found that many of the IUGR babies have demonstrated a short FL with no Downs, and he's actually going to document back that FL & Downs shouldn't necessarily be linked in IUGR babies.

Status: Offline

Oct 13th, 2009, 06:30 AM	#19
nellis10 Trying to conceive (TTC) BnB Addict Join Date: Apr 2008 Location: Belfast Posts: 3,377	Hi Hunnie! With my first I did the tests and got a 1 in 95 chance of down's. It devastated us, but we decided against going for Amnio, and although the rest of the pregnancy was tinged with worry about the possibility, we had a very healthy boy who is now a 5yr old cheeky monkey!

Status: Offline

Oct 14th, 2009, 15:00 PM	#20
blackthickpea Pregnant (Expecting) Active BnB Member Join Date: Jun 2009 Location: Caribbean Posts: 184	i was sent for my quad test at 15 weeksconfirmed gestational age by ultrasound. at the lab the tech used my LMP date which I advised her not to use cause it would put me at 21.6 weeks when was actually 15. i have very irregular periods due to polycystic ovaries anyway the test came back positive for downs. My doc is being an ass about it. I was told that it came back positive because of the wrong gestational age. i did 2 anomally scans at 20weeks by different specialist but they both came back normal. What do you ladies think? i live in the caribbean and we donot have expertise like the states, united kingdom or Canada. ladies please let me know what you all think. thanksI am so worried I am now 33 weeks

Status: Offline

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